产品货号：
Z31228
中文名称：
DICER1抗体
英文名称：
Anti-DICER1 Antibody (Clone#OTI1E11)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DICER1 Antibody (Clone#OTI1E11) |
| 指标别名 | DCR1;Dicer;dicer 1;ribonuclease type III;DICER1;Endoribonuclease Dicer;Helicase MOI;Helicase with RNase motif;HERNA;KIAA0928 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC |
| 基因名称 | DICER1 |
| 克隆号 | OTI1E11 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1666-1922 of human DICER1 (NP_085124) produced in E.coli. |
| 实际分子量 | 218.5KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Dicer(DICER1),also known as endoribonuclease Dicer or helicase with RNase motif,is an enzyme that in humans is encoded by the DICER1 gene.It is mapped to 14q32.13.The DICER1 gene,a member of the ribonuclease III (RNaseIII) family,is involved in the generation of microRNAs (miRNAs),which modulate gene expression at the posttranscriptional level.DICER1 possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus DICER,also known as helicase-MOI,is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression.In addition,DICER1 is required for formation of the RNA induced silencing complex (RISC).It also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. |
| Uniprot ID | Q9UPY3 |
| 基因名全称 | dicer 1,ribonuclease III |
| 蛋白名全称 | Endoribonuclease Dicer |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索：DICER1抗体，DICER1单抗，Anti-DICER1 Antibody (Clone#OTI1E11)